• p90-120

MAJOR LINKS FOR CDw12  

• No information

CELLULAR FUNCTION OF CDw12   - No information

DISEASE RELEVANCE OF CDw12 AND FUNCTION OF CDw12 IN INTACT ANIMAL   - No information

MOLECULAR STRUCTURE OF CDw12  

• A detailed structure has not been determined (not cloned)
• CDw12 is a phosphoprotein.

MOLECULAR MASS OF CDw12  

POST-TRANSCRIPTIONAL MODIFICATION OF CDw12   - No information

POST-TRANSLATIONAL MODIFICATION OF CDw12   - phosphorylation

SUBSTRATES FOR CDw12   - No information

ENZYMES WHICH MODIFY CDw12   - No information

LIGANDS FOR CDw12 AND MOLECULES ASSOCIATED WITH CDw12   - No information

• CDw12 is present on monocytes, granulocytes, and NK cells
• CDw12 is absent from basophils, AML blasts, and bone marrow precursors.

SELECTION OF OTHER CDw12-SPECIFIC REFERENCE MAB  

REVIEWS

PRIMARY CITATIONS

1. Bernard A. In Leukocyte Typing (ed A. Mernard et al), p. 82, Springer-Verlag, Berlin (1984)

2. Knapp W. In Leukocyte Typing IV (ed. W. Knapp et al.) pp. 781. OxfordUniversity Press, Oxford (1989)

3. Marinov J,Koubek K,Stary J Expression of CDw12 and CD17 cell surface antigens on leukemic cells from patients with blood malignancies. Folia Biol (Praha) 1993 39:124 PubMed

4. Pui CH,Behm FG,Singh B,Rivera GK,Schell MJ,Roberts WM,Crist WM,Mirro J Jr Myeloid-associated antigen expression lacks prognostic value in childhood acute lymphoblastic leukemia treated with intensive multiagent chemotherapy. Blood 1990 75:198 PubMed

5. Stain C,Stockinger H,Scharf M,Jager U,Gossinger H,Lechner K,Bettelheim P Human blood basophils display a unique phenotype including activation linked membrane structures. Blood 1987 70:1872 PubMed

6. van der Schoot, C.E. et al. In Leukocyte Typing IV (ed. W. Knapp et al.) pp.868-76. Oxford University Press, Oxford (1989)

WWW RESOURCES

Portions copyright by Garland Press and by the International Workshops on Human Leukocyte Differentiation Antigens; used with permission

Modified 10/14/99   mpr@mail.nih.gov