• From: Kevin Lewis Otipoby     Date: 04/09/98
  Subject: CD22 deficient mice

  The following three papers describe CD22-deficient mice.

  Otipoby KL, Andersson KB, Draves KE, Klaus SJ, Farr AG, Kerner JD, Perlmutter RM, Law CL and Clark EA. CD22 regulates thymus-independent responses and the lifespan of B cells. Nature 1996 384:634 PubMed

  O'Keefe TL, Williams GT, Davies SL and Neuberger MS. Hyperresponsive B cells in CD22-deficient mice. Science 1996 274:798 PubMed

  Sato S, Miller AS, Inaoki M, Bock CB, Jansen PJ, Tang ML and Tedder TF. CD22 is both a positive and negative regulator of B lymphocyte antigen receptor signal transduction: altered signaling in CD22-deficient mice. Immunity 1996 5:551 PubMed
  
  

Modified 10/14/99   mpr@mail.nih.gov