p-Akt1/2/3 (Ser 473)-R is provided by Santa Cruz Biotechnologies
| Antibody Name | p-Akt1/2/3 (Ser 473)-R |
|---|---|
| AntibodyPhosphoID | 1308 |
| Polyclonal | |
| Species | Rabbit |
| Sequence Representative | FPQFpSYSAS |
|---|---|
| Company Name | Santa Cruz Biotechnologies |
| Catalog #: Primary | sc-7985-R |
| Catalog #: Other | 7985 |
| Derived Url | http://www.scbt.com/product.php?datasheet=7985 |
| Withdrawn? | false |
| Designated Phosphorylation Sites | |||||
|---|---|---|---|---|---|
| Gene/Protein | Phosphorylation Sites | ||||
|
Symbol
Name |
Site Name | Alt Res Names | Local Sequence | MPR Site ID | Refs |
|
AKT3
AKT3 
|
|||||
| S472 | FPQFpSYSAS | 897 | |||
|
AKT1
Akt1
|
|||||
| S473 | FPQFpSYSAS | 12 | |||
|
AKT2
Akt2
|
|||||
| S474 | FPQFpSYSAS | 896 | |||
- Brognard J, Clark AS, Ni Y, Dennis PA. 2001. Akt/protein kinase B is constitutively active in non-small cell lung cancer cells and promotes cellular survival and resistance to chemotherapy and radiation. Cancer Res 61:3986-3997 (Abstract) [site(s): S473]
- Kitaura J, Asai K, Maeda-Yamamoto M, Kawakami Y, Kikkawa U, Kawakami T. 2000. Akt-dependent cytokine production in mast cells. J Exp Med 192:729-740 (Abstract) [site(s): S473]
- Kroner C, Eybrechts K, Akkerman JW. 2000. Dual regulation of platelet protein kinase B. J Biol Chem 275:27790-27798 (Abstract) [site(s): S473]
- Lynch DK, Ellis CA, Edwards PA, Hiles ID. 1999. Integrin-linked kinase regulates phosphorylation of serine 473 of protein kinase B by an indirect mechanism. Oncogene 18:8024-8032 (Abstract) [site(s): S473]
- Rane MJ, Coxon PY, Powell DW, Webster R, Klein JB, Ping P, Pierce W, McLeish KR. 2000. p38 KINASE-DEPENDENT MAPKAPK-2 ACTIVATION FUNCTIONS AS PDK2 FOR AKT IN HUMAN NEUTROPHILS. J Biol Chem : (Abstract) [site(s): S473]
- Shan X, Czar MJ, Bunnell SC, Liu P, Liu Y, Schwartzberg PL, Wange RL. 2000. Deficiency of PTEN in Jurkat T cells causes constitutive localization of Itk to the plasma membrane and hyperresponsiveness to CD3 stimulation. Mol Cell Biol 20:6945-6957 (Abstract) [site(s): S473]
- Stokoe D, Stephens LR, Copeland T, Gaffney PR, Reese CB, Painter GF, Holmes AB, McCormick F, Hawkins PT. 1997. Dual role of phosphatidylinositol-3,4,5-trisphosphate in the activation of protein kinase B. Science 277:567-570 (Abstract) [site(s): S473]
- Toker A, Newton AC. 2000. Akt/protein kinase B is regulated by autophosphorylation at the hypothetical PDK-2 site. J Biol Chem 275:8271-8274 (Abstract) [site(s): S473]